Alesse (Levonorgestrel/Ethinyl estradiol)

Active Ingredient: Levonorgestrel/Ethinyl estradiol

Dosages: 0.15/0.03mg, 0.25/0.05mg

1. Drug Description

Alesse (levonorgestrel and ethinyl estradiol): Alesse is an oral contraceptive pill that combines two active ingredients, levonorgestrel (a progestin) and ethinyl estradiol (an estrogen). It is available in a tablet form.

Mechanism of Action: Alesse works by preventing the release of an egg from the ovary (ovulation) and by thickening the cervical mucus, which makes it difficult for sperm to reach the egg. It also changes the lining of the uterus, making it less receptive to a fertilized egg. These actions combined help to prevent pregnancy.

Effectiveness: When used consistently and correctly, Alesse has a high effectiveness rate in preventing pregnancy. According to clinical studies, the failure rate of Alesse is less than 1% when used consistently and correctly. It is important to note that missing pills, taking pills at irregular times, or certain medications can reduce its effectiveness.

Side Effects: Like any medication, Alesse can cause side effects. Common side effects may include nausea, vomiting, headache, breast tenderness, changes in weight or appetite, mood changes, and irregular bleeding or spotting between periods. These side effects are usually mild and often resolve on their own. However, if any of these side effects persist or become severe, it is important to consult a healthcare professional.

Potential Risks: While Alesse is generally safe and well-tolerated, it is important to be aware of the potential risks associated with its use. A small percentage of women may experience more serious side effects, such as blood clots, stroke, heart attack, liver disease, or high blood pressure. Smoking, obesity, and certain medical conditions may increase the risk of these complications. It is important to discuss any pre-existing health conditions or concerns with a healthcare professional before starting Alesse.

Precautions and Contraindications: There are certain precautions and contraindications associated with the use of Alesse. It is not recommended for women who are pregnant or breastfeeding. It should also be avoided by women who have a history of blood clots, certain cancers, liver disease, or uncontrolled high blood pressure. Additionally, Alesse may interact with certain medications, such as antibiotics, antifungals, antiepileptics, and HIV medications. It is important to inform a healthcare professional about all current medications, including over-the-counter drugs and herbal supplements, before starting Alesse.

Purchase History of Alesse

Development and FDA Approval

Alesse, a combination hormonal contraceptive, was developed by Wyeth Pharmaceuticals and received FDA approval in the United States in 1997. It is a prescription medication that contains two active ingredients, ethinyl estradiol and levonorgestrel.

Market Availability and Popularity

Since its introduction, Alesse has become a popular oral contraceptive choice for women. It is widely available in pharmacies and online platforms. The convenience and effectiveness of Alesse have contributed to its widespread use as a preferred method of birth control.

Formulation Changes and Packaging Updates

Over the years, Alesse has undergone formulation changes and packaging updates to enhance its user experience. These updates include improvements such as simplified pill organization and packaging designs that are easier to use and understand.

Recalls and Safety Concerns

While Alesse has proven to be a generally safe and effective contraceptive, there have been occasional recalls and safety concerns associated with the medication. These incidents are rare and are typically addressed promptly by the manufacturer and regulatory authorities to ensure patient safety.

For more information on the development, FDA approval, market availability, and safety updates of Alesse, please visit the official website of the U.S. Food and Drug Administration (FDA).

Source: Alesse Prescribing Information


Alesse (Levonorgestrel/Ethinyl estradiol)

Active Ingredient: Levonorgestrel/Ethinyl estradiol

Dosages: 0.15/0.03mg, 0.25/0.05mg

Online Medication Purchasing Statistics

As the world becomes increasingly digital, more and more people are turning to online pharmacies to purchase their medications. In the United States, the trend of purchasing medication online has been on the rise in recent years. According to a survey conducted by the National Association of Boards of Pharmacy (NABP), 22% of American adults reported that they had purchased prescription medications online in the past.

There are several reasons why online pharmacies have gained popularity. One of the main advantages is the convenience they offer. Individuals can order their medications from the comfort of their own homes, saving them time and effort. Online pharmacies also provide a discreet way to obtain medications that individuals may feel uncomfortable discussing in person.

Another significant factor driving the popularity of online medication purchasing is cost savings. Online pharmacies often offer lower prices compared to traditional brick-and-mortar pharmacies. This is due to several factors, such as reduced overhead costs and the ability to offer medications in bulk. In some cases, individuals without health insurance may find online pharmacies to be a more affordable option for obtaining their medications.

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Accessibility is another benefit of online pharmacies. They provide individuals in rural or remote areas with access to a wide range of medications that may not be readily available in their local pharmacies. Online pharmacies also offer a wider selection of generic medications, which are often more affordable than their brand-name counterparts.

While online pharmacies offer several advantages, it’s important to be aware of the potential risks and concerns associated with purchasing medications online. One significant risk is the presence of counterfeit drugs. According to the World Health Organization (WHO), an estimated 10% of medications worldwide are counterfeit, and many of these counterfeit drugs are sold online. These medications can be ineffective, unsafe, or even harmful to individuals who take them.

To ensure the safety and effectiveness of the medications they sell, individuals should only purchase from reputable online pharmacies. The U.S. Food and Drug Administration (FDA) and the NABP have established programs to verify the legitimacy of online pharmacies. They provide a list of verified online pharmacies on their websites, which individuals can use as a resource when making their purchasing decisions.

In addition, individuals should always consult with their healthcare professionals or pharmacists before making any changes to their medication regimen. They can provide guidance and help individuals make informed decisions about purchasing their medications online.

In conclusion, online medication purchasing is on the rise in the United States due to the convenience, cost savings, and accessibility it offers. However, individuals need to be cautious and ensure they are purchasing from reputable online pharmacies to avoid the risks associated with counterfeit drugs. Consulting healthcare professionals or pharmacists is crucial to ensure the safe and effective use of medications purchased online.

Generic Drug Manufacturers

What are generic drugs?

Generic drugs are medications that contain the same active ingredients as their brand-name counterparts and have the same strength, dosage form, and route of administration. They are typically produced after the patent for the brand-name drug has expired, allowing other pharmaceutical companies to manufacture and sell generic versions.

Generic drugs provide affordable alternatives to brand-name medications, as they are often priced significantly lower. They undergo rigorous testing by regulatory authorities to ensure their safety, efficacy, and bioequivalence to the brand-name drug.

Manufacturers of generic Alesse

Several pharmaceutical companies produce generic versions of Alesse. Some of the prominent manufacturers include:

These manufacturers are well-established and reputable in the pharmaceutical industry, ensuring that the generic versions of Alesse meet the necessary quality standards and regulations.

Regulatory processes and standards for generic drugs

Generic drugs go through an approval process to ensure their safety and effectiveness. The regulatory processes and standards vary across different countries, but they typically involve evaluating the bioequivalence of the generic drug to the brand-name drug.

In the United States, the U.S. Food and Drug Administration (FDA) regulates the approval of generic drugs. The FDA requires generic drugs to demonstrate bioequivalence to the brand-name drug, meaning that they must have the same rate and extent of absorption in the body.

To gain FDA approval, generic drug manufacturers must submit an Abbreviated New Drug Application (ANDA), which includes data from bioequivalence studies. The FDA reviews the data to ensure that the generic drug is therapeutically equivalent to the brand-name drug.

Efficacy and cost difference between generic and brand-name Alesse

Generic versions of Alesse have been shown to be as effective as the brand-name drug in preventing pregnancy. They contain the same active ingredients, norgestimate and ethinyl estradiol, in the same amounts.

Cost is often a significant factor when considering medication options. Generic drugs tend to be more affordable than brand-name drugs, making them a cost-effective choice for many individuals. The prices of generic Alesse may range from $15 to $30 for a month’s supply depending on the pharmacy and location.

It is worth noting that even though generic drugs are cheaper, they are manufactured using the same quality standards as brand-name drugs. Therefore, individuals can expect the same level of safety and effectiveness when choosing a generic version of Alesse.

Correct Medication Usage

It is essential to use Alesse correctly to ensure its optimal contraceptive effectiveness. Here are step-by-step instructions on how to properly use Alesse:

Dosage Instructions

Alesse is an oral contraceptive that comes in the form of tablets. Each pack contains 28 tablets, with 21 active hormone tablets and 7 inactive reminder tablets. It is crucial to follow the prescribed dosage of Alesse as instructed by your healthcare provider.

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On the first day of your menstrual period, start taking the active hormone tablets. Take one tablet at the same time every day, preferably with a glass of water. It is essential to take the tablets consistently, without skipping any doses.

After finishing the active hormone tablets, continue taking the inactive reminder tablets for the next 7 days. These reminder tablets do not contain any active hormones but are included to help maintain a regular schedule and remind you to start the next pack.

Once you finish all 28 tablets, start a new pack of Alesse right away, without any gaps in between packs.

Timing and Missed Pill Guidelines

Timing: Take Alesse tablets at the same time every day to maintain a consistent hormone level in your body. Setting a reminder or using an alarm can help you remember to take your daily dose.

Missed Pills: In case you miss a pill, follow these guidelines:

  • If you missed one active hormone pill, take it as soon as you remember, even if it means taking two pills on the same day. Continue taking the remaining pills at the usual time. No backup contraception is necessary.
  • If you missed two consecutive active hormone pills in the first or second week of your pack, take two pills as soon as you remember and two pills the following day. Use backup contraception, such as condoms or spermicide, for the next 7 days.
  • If you missed two consecutive active hormone pills in the third week of your pack or three or more consecutive active hormone pills at any time, discard the remaining pills and start a new pack right away. Use backup contraception for the next 7 days.
  • If you missed any of the inactive reminder pills, discard them and continue with the next pack as scheduled. No backup contraception is necessary.
  • Always refer to the patient information leaflet or consult your healthcare provider for specific instructions in case of missed pills.

Menstrual Periods: Alesse can help regulate your menstrual periods and may make them lighter, shorter, and less painful. Some women may experience breakthrough bleeding or spotting while taking Alesse. If this happens, continue taking the pills as scheduled. If the bleeding persists or is very heavy, consult your healthcare provider.

Interactions with Other Medications

Alesse may interact with certain medications, affecting its effectiveness or increasing the risk of side effects. Some medications that may interact with Alesse include:

  • Antibiotics, such as rifampicin, rifabutin, or griseofulvin.
  • Anticonvulsants, such as phenytoin, carbamazepine, or topiramate.
  • Antifungal medications, such as ketoconazole or itraconazole.
  • HIV medications, such as ritonavir.
  • St. John’s Wort, a herbal supplement.

Inform your healthcare provider about all medications, supplements, or herbal products you are taking to ensure there are no potential interactions with Alesse.

Starting or Stopping Alesse

If you are starting Alesse for the first time, your healthcare provider may recommend starting on the first day of your menstrual period. However, they may also suggest starting Alesse at any other time if it is unlikely that you are pregnant.

If you are switching from another oral contraceptive to Alesse, follow your healthcare provider’s instructions carefully to ensure a smooth transition.

If you decide to stop taking Alesse, consult your healthcare provider. It is essential to discuss alternative contraceptive options and develop a plan that suits your individual needs.

Lifestyle Factors and Behaviors

Several lifestyle factors and behaviors may affect the efficacy of Alesse or any other oral contraceptive. These include:

  • Smoking: Smoking while taking Alesse increases the risk of serious cardiovascular side effects.
  • Alcohol Consumption: Heavy alcohol consumption may decrease the effectiveness of Alesse.
  • Other Medications: Certain medications, such as some anticonvulsants or antifungal medications, may interact with Alesse.

It is important to discuss your lifestyle factors and any medications you are taking with your healthcare provider to ensure the safe and effective use of Alesse.

Remember, this information is provided as a general guide, and it is important to consult your healthcare provider or pharmacist for personalized instructions and advice regarding the correct usage of Alesse.


Alesse (Levonorgestrel/Ethinyl estradiol)

Active Ingredient: Levonorgestrel/Ethinyl estradiol

Dosages: 0.15/0.03mg, 0.25/0.05mg

Other Brands Similar to Alesse

When it comes to oral contraceptives, Alesse is just one of many options available in the market. Here are some other brand-name oral contraceptives that are similar to Alesse:

  1. Aviane: Aviane is a brand-name oral contraceptive that contains the same active ingredients as Alesse, namely ethinyl estradiol and levonorgestrel. It is available in a 21-day pack, with a reminder pill to be taken for 7 days. Aviane is known for its effectiveness in preventing pregnancy and its relatively low risk of side effects. Like Alesse, it is widely used and trusted by women around the world.
  2. Loestrin: Loestrin is another brand-name oral contraceptive that is similar to Alesse. It also contains ethinyl estradiol and levonorgestrel as its active ingredients. Loestrin is available in both a 21-day pack and a 28-day pack, offering greater flexibility for women who prefer a shorter or longer menstrual cycle. It is known for its convenience and ease of use.
  3. Microgestin: Microgestin is a brand-name oral contraceptive that contains the same active ingredients as Alesse, ethinyl estradiol and levonorgestrel. It is available in a 21-day pack, with a 7-day reminder pill. Microgestin is known for its affordability and accessibility, making it a popular choice for women who are looking for a cost-effective contraceptive option.
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These brand-name oral contraceptives have similar effectiveness in preventing pregnancy and share common side effects and precautions with Alesse. However, it is important to note that individual responses to different brands may vary, so it is essential to consult with a healthcare professional before choosing the right contraceptive option.

When considering these alternative brands, it is also worth mentioning their generic counterparts. Generic versions of oral contraceptives are more cost-effective and offer the same active ingredients and efficacy as their brand-name counterparts. Some manufacturers that produce generic versions of Alesse and its alternatives are:

Generic Drug Manufacturer Brand Equivalent
Teva Pharmaceuticals Alesse, Aviane
Mylan Pharmaceuticals Alesse, Loestrin
Glenmark Pharmaceuticals Alesse, Microgestin

Generic versions offer a more affordable option for women seeking reliable contraception. They undergo rigorous testing to ensure their safety, efficacy, and bioequivalence to the brand-name drug. This means that they are virtually identical to the brand-name drug in terms of quality, dosage, strength, and administration. Choosing a generic version may provide significant cost savings while maintaining the same level of effectiveness.

When it comes to choosing between brand-name oral contraceptives like Alesse and its alternatives, it ultimately depends on individual preferences, needs, and healthcare considerations. Consulting a healthcare professional or pharmacist can provide personalized guidance and support in making the right contraceptive choice.

For further information on Alesse, its alternatives, or generic oral contraceptives, you can visit reputable online pharmacies and healthcare websites such as WebMD and


In conclusion, Alesse is an oral contraceptive pill that contains the active ingredients ethinyl estradiol and levonorgestrel. It works by preventing ovulation, thickening the cervical mucus to inhibit sperm from reaching the egg, and thinning the lining of the uterus to prevent implantation of a fertilized egg. Alesse is a highly effective method of preventing pregnancy when taken correctly.

Like any medication, Alesse may cause side effects in some individuals. Common side effects may include nausea, headache, breast tenderness, and breakthrough bleeding. It is important to note that the risks associated with using Alesse, such as blood clots, are generally low and depend on individual factors such as age, smoking status, and medical history.

Before using Alesse, it is essential to consult a healthcare professional or pharmacist to assess any potential contraindications, allergies, or interactions with other medications. Additionally, it is important to follow the instructions for use carefully, including taking the pill at the same time each day and starting a new pack promptly to maintain optimal contraceptive effectiveness.

When purchasing medication online, it is crucial to ensure the safety and legitimacy of the online pharmacy. Look for reputable websites that require a prescription and have a verified seal from the National Association of Boards of Pharmacy (NABP) or Verified Internet Pharmacy Practice Sites (VIPPS). It is also recommended to compare prices and check customer reviews before making a purchase.

Generic versions of Alesse, such as Aviane and Lutera, are available at a lower cost compared to the brand-name medication. These generic versions contain the same active ingredients and meet the same rigorous regulatory standards as the brand-name drug. Therefore, they are considered safe and effective alternatives.

In conclusion, Alesse is a widely used oral contraceptive that offers an effective and convenient method of birth control. However, it is important to consider individual preferences and healthcare needs when choosing a contraceptive method. Consulting a healthcare professional is crucial to ensure the safety and appropriateness of Alesse or any other medication.

For more information on Alesse or other oral contraceptive options, please refer to the following reputable sources:

Category: Alesse | Tags: Alesse, Levonorgestrel/Ethinyl estradiol